Medicine recalls, shortages and safety updates in the UK — December 2025

MHRA medicines recalls and defect notifications with batch numbers, Serious Shortage Protocols, new approvals and Drug Safety Update — updated daily, automatically. Last updated: 27 Sep 2026 13:39.

All Recalls and defects2 Serious shortages (SSP)2 New approvals1 Drug Safety Update1

Sources: we track changes based on information published by the MHRA — medicines recalls and defect notifications, Drug Safety Update and approval announcements — and the Serious Shortage Protocols published by the NHS Business Services Authority. The UK is outside the EU, so European Commission decisions are not listed here.

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4 Dec 2025Thursday 4 December 2025

open day ◀ ▶ 1 event · 1 important

Drug Safety Update Mesalazine and idiopathic intracranial hypertension

Idiopathic intracranial hypertension (IIH) has been very rarely reported in patients treated with mesalazine. Following a recent review, warnings for IIH are being added to the product information for…

What this means, batches, details

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details and permanent link Drug Safety Update on GOV.UK ↗ MHRA — Medicines and Healthcare products Regulatory Agency

2 Dec 2025Tuesday 2 December 2025

open day ◀ ▶ 1 event

MHRA approval tisotumab vedotin

As with all licensed medicines, we will continue to monitor its safety closely as it becomes more widely used

What this means, batches, details

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details and permanent link MHRA announcement ↗ MHRA — Medicines and Healthcare products Regulatory Agency

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In total 10 events this month.

Key

class 1 recall (risk to life)

class 2–3 recall, serious shortage, safety update

class 4 defect notification, new approval

A batch recall does not mean the medicine is withdrawn: it remains licensed, only the listed batches are affected.

Sources

MHRA alerts — medicines recalls and defect notifications since January 2024.
Drug Safety Update.
Serious Shortage Protocols (NHSBSA).